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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
21.82
Human Site:
T445
Identified Species:
43.64
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
T445
K
K
R
Q
S
D
D
T
L
C
R
F
E
S
V
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
T446
K
K
R
Q
S
D
D
T
L
C
R
F
E
S
V
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
T429
K
K
R
Q
S
D
D
T
L
C
R
F
E
S
V
Dog
Lupus familis
XP_538964
685
76968
T498
K
K
R
Q
S
E
E
T
L
C
R
F
E
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
T442
K
K
R
Q
S
D
D
T
L
C
R
F
E
S
V
Rat
Rattus norvegicus
Q62726
629
70550
P442
K
K
R
Q
S
D
D
P
L
C
R
F
E
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
D439
A
K
D
S
S
F
S
D
P
D
P
A
P
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
Q113
S
Y
L
F
Q
L
L
Q
G
L
A
F
C
H
S
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
S445
S
R
L
N
Q
S
D
S
S
H
Q
S
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
N385
K
I
V
P
E
N
V
N
S
K
L
V
P
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
S392
T
G
K
K
V
E
D
S
W
D
D
F
D
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
P258
T
R
I
A
D
L
L
P
N
A
A
P
E
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
100
86.6
N.A.
100
93.3
N.A.
13.3
N.A.
6.6
13.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
N.A.
6.6
33.3
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
9
17
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
9
0
0
% C
% Asp:
0
0
9
0
9
42
59
9
0
17
9
0
9
0
0
% D
% Glu:
0
0
0
0
9
17
9
0
0
0
0
0
59
9
9
% E
% Phe:
0
0
0
9
0
9
0
0
0
0
0
67
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
59
59
9
9
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
17
0
0
17
17
0
50
9
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
17
9
0
9
9
17
0
0
% P
% Gln:
0
0
0
50
17
0
0
9
0
0
9
0
0
0
0
% Q
% Arg:
0
17
50
0
0
0
0
0
0
0
50
0
0
0
9
% R
% Ser:
17
0
0
9
59
9
9
17
17
0
0
9
0
59
25
% S
% Thr:
17
0
0
0
0
0
0
42
0
0
0
0
9
0
0
% T
% Val:
0
0
9
0
9
0
9
0
0
0
0
9
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _